Attendees weren’t just scientists and people from the pharmaceutical industry. They also included, on one day of the event, families of patients with epilepsy.
It’s been my experience that right now Drs. ( vets also ) don’t have a lot of CBD knowledge. It was pain and depression so I wasn’t hanging onto the Epilepsy details. Charotte’s Web was what I was interested in and that when I starting reading the Epilepsy stuff. So please, please research this CBD gummies for sale first without just taking my word for it. You might even come across more detailed information and maybe even a suggested dose.
Potentially, CBD can increase the duration and strength of ibuprofen, thereby increasing the risk of adverse side effects. No human studies to date examine CBD’s interaction with NSAIDs specifically. Still, two studies conducted on animal models in 2006 and 2008 and published respectively in the journals, Pain and Pharmacology, suggest that other cannabinoids may work synergistically with NSAIDs like ibuprofen to reduce pain. Ibuprofen is a nonsteroidal anti-inflammatory (NSAID) medicine that reduces pain and inflammation in the body.
But these problems are seen only when very high doses of CBD (20-50 mg/kg) are given along with other drugs. One of the only established harmful effects of CBD is the modulation of liver enzymes. High doses of CBD — a few hundred or thousand milligrams taken orally — can inhibit drug-metabolizing enzymes.
A lack of federal regulation (for now at least) of the CBD space enables such false advertising—and also makes it difficult to know what other substances might be in any given CBD product. Each additional unknown substance could raise its own drug-drug interaction concerns. No one has systematically studied CBD’s interactions with other drugs. The only clear documentation of interactions comes from studies on Epidiolex, a federally approved treatment for a few rare forms of epilepsy made primarily of concentrated CBD. Those studies found that particularly high CBD doses could, in some patients, increase blood levels of other antiepileptics they were taking, such as clobazam, eslicarbazepine, rufinamide, topiramate, valproate, and zonisamide.